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Beta glucan 1,3/1,6D - Action and Properties

Beta glucan 1,3/1,6D - Action and Properties

Beta-glucan 1,3/1,6D is a compound of natural origin that is gaining increasing popularity in medicine, dietetics and cosmetology. Its unique chemical structure and wide range of biological properties make it a valuable component for supporting health. This polysaccharide is mainly found in the cell walls of fungi, yeast and some plants and is valued for its immunomodulatory, antioxidant and anti-inflammatory properties.

In recent years, ongoing scientific research has confirmed that beta-glucan 1,3/1,6D can support the functioning of the immune system, increasing the body's resistance to infection and supporting recovery from disease. In addition, its use in cosmetics and dietary supplements has benefits in improving skin condition, reducing inflammation and supporting repair processes.

In this article we will discuss the mechanisms of action of beta-glucan 1,3/1,6D, its properties and practical applications in various areas of life, from health to body care. Find out why you should pay attention to this remarkable ingredient and what benefits its regular use can bring.

What are Beta glucan 1,3/1,6D?

Beta-glucan 1,3/1,6D is a type of polysaccharide, a carbohydrate compound made up of long chains of glucose. It is distinguished by its unique chemical structure, in which glucose units are linked by β-1,3 and β-1,6 bonds. This specific configuration makes beta-glucan 1,3/1,6D have unique biological properties, which have found applications in medicine, dietetics and cosmetology.

The compound occurs naturally in the cell walls of yeast, fungi, some bacteria, as well as oats and barley. Particularly valuable sources of beta-glucan 1,3/1,6D are mushrooms, such as oyster mushrooms and shiitake, as well as the yeast Saccharomyces cerevisiae.

Beta-glucan is valued primarily for its immunomodulatory effects, meaning that it can support and regulate the functioning of the immune system. As a result, it is used in the prevention and treatment of infections, as well as to support the body during anti-cancer therapies. In addition, beta-glucan 1,3/1,6D exhibits anti-inflammatory and antioxidant properties, as well as supporting tissue regeneration, making it a versatile ingredient in health and beauty products.

Beta glucan 1,3/1,6D - Chemical Composition

Beta-glucan 1,3/1,6D is a polysaccharide whose basic structural unit is glucose, a simple sugar belonging to the group of monosaccharides. The key feature of beta-glucan 1,3/1,6D is the specific arrangement of glycosidic bonds between glucose molecules. The main chain consists of glucose linked by β-1,3 bonds, while the side branches are attached by β-1,6 bonds. This unique structure distinguishes it from other beta-glucans, such as those found in oats (β-1,3/1,4).

The chemical structure of beta-glucan 1,3/1,6D determines its ability to interact with cell receptors in the immune system. These receptors, such as Dectin-1, recognize and bind beta-glucan molecules, leading to the activation of the immune response.

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In addition, the specific structure of beta-glucan makes it hydrophilic, allowing it to bind water and form gels. As a result, it also shows potential for applications in the food and cosmetic industries, where it acts as a stabilizer or moisturizing ingredient.

From a chemical point of view, beta-glucan 1,3/1,6D is a macromolecule whose molecular weight can vary depending on the source of origin and method of isolation. Its natural sources, such as yeast (Saccharomyces cerevisiae) or fungi, provide a variety of forms of this compound, which can vary in chain length and degree of branching, which affects their bioactivity.

It is because of this chemical complexity that beta-glucan 1,3/1,6D has earned its status as one of the most important natural ingredients for supporting the body's health and regeneration.

Beta glucan 1,3/1,6D - Action

Strengthening the Immune System - Beta glucan 1,3/1,6D

Beta-glucan 1,3/1,6D is a natural immunomodulator distinguished by its ability to support and regulate immune system function. Its action is based on interaction with receptors of immune system cells, which initiates a series of reactions that enhance the immune response.

The main mechanism of action of beta-glucan is activation of Dectin-1 receptors present on the surface of macrophages, neutrophils and dendritic cells. After binding to the receptor, beta-glucan stimulates these cells to produce cytokines - proteins that play a key role in communication between immune cells. Through this process, the body's ability to recognize and eliminate pathogens such as bacteria, viruses and fungi increases.

Anticancer Activity - Beta glucan 1,3/1,6D

Beta-glucans are being intensively studied for their potential anticancer properties. Research suggests that beta-glucans may inhibit the growth of cancer cells and promote the process of apoptosis (programmed cell death), which helps the body fight tumors naturally. In particular, beta-glucans, with a beta-1,3/1,6 structure, present in fungi such as Coriolus versicolor, are being widely studied as adjuncts to anti-cancer therapies. In Japan, beta-glucans are used as an adjunct to traditional cancer therapies.

Anti-inflammatory effect - Beta glucan 1,3/1,6D

Beta-glucans also have anti-inflammatory properties, making them a valuable support in the treatment of chronic inflammatory diseases. They work by inhibiting the production of pro-inflammatory cytokines, which reduces inflammation in the body. As a result, beta-glucans can be helpful in alleviating the symptoms of conditions such as arthritis, autoimmune diseases, as well as other conditions associated with an excessive inflammatory response.

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Lowering Cholesterol Levels - Beta glucan 1,3/1,6D

Beta-glucans derived from oats and barley (mainly with a beta-1,4 structure) have the ability to lower blood cholesterol levels. They work by binding cholesterol in the intestines and inhibiting its absorption, leading to a reduction in the concentration of LDL ("bad" cholesterol) in the blood. Therefore, regular consumption of beta-glucans can support cardiovascular health and reduce the risk of atherosclerosis.

Regulation of Glucose Metabolism - Beta glucan 1,3/1,6D

Beta-glucans can also help regulate blood sugar levels. Due to their fiber properties, beta-glucans slow the absorption of glucose, which helps stabilize blood sugar levels after meals. This action is particularly beneficial for people with type 2 diabetes or insulin resistance, as it can promote glycemic control.

Use of Beta-glucans in Medicine and Supplementation - Beta glucan 1,3/1,6D

Beta-glucans are widely used in dietary supplements and medical products. They are available in the form of capsules, powders and extracts of medicinal mushrooms, such as Coriolus versicolor, Reishi or Maitake. These supplements are particularly popular among those seeking natural remedies to support immunity, support cancer therapies and improve cardiovascular health.

The company offers ENCANN product available Coriolus Wrośniak Multicolored, which contains beta-glucan-rich extract from the mushroom Coriolus versicolor. This supplement supports the health of the immune system, as well as acts as an aid in anti-cancer therapy, making it an excellent choice for those who care about their health

 

Beta glucan 1,3/1,6D - Summary

Beta-glucan 1,3/1,6D is a natural compound with exceptional health-promoting properties, which is gaining increasing recognition in medicine, dietetics and cosmetology. Thanks to its specific chemical structure - the combination of β-1,3 bonds in the main chain with β-1,6 side branches - it exhibits strong immunomodulatory, antioxidant and anti-inflammatory effects.

Key benefits of beta-glucan 1,3/1,6D:

  1. Strengthening the immune system - Supports the body in fighting infections by stimulating macrophages, lymphocytes and other immune cells.
  2. Anti-inflammatory effect - helps regulate the body's inflammatory response, which promotes health and tissue regeneration.
  3. Recovery support - Accelerates repair processes after illness, stress or intense exercise.
  4. Cosmetic use - moisturizes, regenerates and protects the skin, making it a valuable ingredient in cosmetics.
  5. Safety of use - Its natural origin and lack of side effects at recommended doses make beta-glucan suitable for a wide range of users.

Thanks to its wide range of activities, beta-glucan 1,3/1,6D can be a valuable addition to the diet, especially during periods of increased risk of infection, such as the autumn and winter seasons. Its presence in dietary supplements, medicinal preparations and cosmetics makes it a versatile support in taking care of health and beauty.

Incorporating beta-glucan 1,3/1,6D into your daily routine can provide measurable health benefits, supporting immunity, improving quality of life and supporting the body in maintaining physiological balance. This is an example of how nature provides solutions to support health in a safe and effective way.

 

 

Source: PubMed (https://pubmed.ncbi.nlm.nih.gov/); Google Scholar (https://scholar.google.com/); National Center for Biotechnology Information (NCBI); ResearchGate (https://www.researchgate.net/)

Statements given refer to research on adaptogens Hericium Erinaceus, Ganoderma Lucidum, Cordyceps Militaris, Ashwagandha and Coriolus Versicolor not over Encann® brand products. These are not claims regarding the medicinal properties of the product offered. In accordance with European Parliament Regulation 1924/2006, verifiable scientific evidence regarding studies on the use of the fungus is presented on this page. Hedgehog soplolly- one of the components of the offered product.